A groundbreaking collaborative project has been launched involving the labs of @BrianHie and Hsu, the @arcinstitute, and @StanfordEng, focusing on the development of biological foundation models. These models aim to integrate DNA, RNA, and protein modalities, covering molecular, systems, and genome levels of scale. This initiative marks a significant advancement in the field, as it represents the first long-context biological foundation model specifically developed for DNA, with contributions from @exnx. The project's potential applications span across drug discovery, agriculture, and sustainability, highlighting its importance in scientific research. Additionally, related efforts in the scientific community include the creation of a synthetic platform for studying the coevolution of interacting proteins, as reported in Science Magazine, and the development of a computational framework for designing new protein-protein interactions.
Scientists last year created a computational framework that designs new protein-protein interactions through sequence analysis, offering a powerful tool to dissect cell processes or engineer cells to perform new functions. @m_madan_babu #NationalProteinDay https://t.co/jxZcTu5o4j https://t.co/d7grJJuz2e
In Science, researchers created a synthetic platform for studying the coevolution of interacting proteins. The platform could prove useful in developing new protein complexes that recognize a variety of molecules. Learn more on #NationalProteinDay: https://t.co/b1OXZmor5e https://t.co/o1pPRGdVtm
A new major collaborative project across the @BrianHie and Hsu labs, @arcinstitute and @StanfordEng - we’re excited for the future of foundation models in biology at Arc! https://t.co/ynYCVNgDML
Biological foundation models are going to be increasingly important scientific tools that can solve problems across drug discovery, agriculture, and sustainability. Huge to see the first long-context biological foundation model developed for DNA - congrats @BrianHie @exnx. https://t.co/2OAM0K9ijm
In some new work (the first from the new lab!), we lay out a vision for a biological foundation model that unites DNA, RNA, and protein modalities and operates at molecular, systems, and genome levels of scale. Blog: https://t.co/zAtUvaP1LS Preprint: https://t.co/H6oV2qS7ll https://t.co/cQ554qZh55