Recent studies have highlighted new insights into Alzheimer's Disease, suggesting a link between toxic short RNAs and the death of brain cells. Researchers from Northwestern University, as reported in Nature Communications, discovered that these toxic RNAs may facilitate the development of Alzheimer's by killing brain cells. Another study emphasized the importance of RNA interference in the disease, indicating that balancing toxic and protective small RNAs could be a novel treatment approach, potentially offering alternatives to amyloid-focused therapies. Nature Medicine highlighted a modeling study that emulated thousands of trials using over a decade's worth of real-world data, resulting in a shortlist of five candidate drugs for repurposing to treat Alzheimer's. GENbio reported on the study linking an increase in toxic RNAs and a decrease in protective RNAs to neuron death in neurodegenerative diseases and aging. BioCentury's proteomics research has identified five subtypes of the disease, suggesting that each subtype may require distinct treatments and safety considerations.
'Plastics pollution led to $250 billion in disease over one year' in the US The surge in plastics production represents “a dangerous and unnatural experiment” “this is an urgent human health problem” https://t.co/PgGVDD02zX
A single one litre bottle of water can contain 240,000 microscopic plastic particles, with unknown consequences for our health. https://t.co/L3G3cOAE08
Scientists from Northwestern University and elsewhere have published details of a study that links short strands of toxic RNAs to brain cell death and DNA damage in Alzheimer’s disease and aged brains. Learn more: https://t.co/wk3YyYzgUd https://t.co/J43Hzs9mUd
Proteomics study identifies five subtypes of Alzheimer’s. Each one may require different treatments and have different safety considerations. https://t.co/VWepvDveOF
Alzheimer’s Disease Linked to Toxic Short RNAs Study links increase in toxic RNAs, decrease in protective RNAs to neuron death in neurodegenerative diseases and aging. Learn more: https://t.co/wk3YyYzgUd https://t.co/J1GTWMbE6a
Pretty soon we're going to discover that dementia rates are exploding because of microplastics and nanonplastics. In the past couple of months we've seen multiple studies show that MPs and NPs encourage formation of amyloid plaques, the cause of Alzheimer's. https://t.co/HBlwxSkurG
⭐Research highlight: A modeling study emulated thousands of trials from over 10 years’ worth of real-world data, generating a shortlist of five candidate drugs for repurposing in #AlzheimersDisease. @NatureComms #RWD https://t.co/oXs8UpQ9L5
A new study finds key role of RNA interference in Alzheimer’s. Balancing toxic & protective sRNAs could be a novel treatment path, offering hope beyond amyloid-focused therapies. https://t.co/4BXkbSIRKw https://t.co/E7aegu5zjC
New study discovers short, toxic RNAs kill #brainCells and may allow Alzheimer's to develop @northwesternu @NatureComms https://t.co/YJChLu1r0w