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Daily market recaps with key events, stock movements, and global influences
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5 posts • OpenAI (o3)
Published
Nearly one-third of U.S. adolescents aged 12 to 17—about 8.4 million youths—had prediabetes in 2023, according to new data from the Centers for Disease Control and Prevention. The analysis of fasting blood-glucose and hemoglobin A1c tests from the National Health and Nutrition Examination Survey found a prevalence rate of 32.7%, indicating blood-sugar levels that are elevated but not yet in the diabetic range.
Read more
When my uncle was president, childhood diabetes was almost unheard of. Now, 1 in 3 kids is diabetic or pre-diabetic. We understand what’s driving this epidemic, and we have the power to stop it. It begins with what we eat. It’s time to take back our children’s health and Make
33% of Americans between 12 and 17 are pre-diabetic, according to CDC statistics. Follow: @AFpost
An estimated 1 in 3 teens and preteens, ages 12 to 17, have prediabetes, according to new data from the CDC.
Nearly 1 in 3 American adolescents have prediabetes, a CDC report finds. An official notes "it’s not too late to change course."
1/3rd of US teens (>8 million kids) have prediabetes
11 posts • OpenAI (o3)
Published
Prices for the two leading obesity injections—Novo Nordisk’s semaglutide shot Wegovy and Eli Lilly’s tirzepatide shot Zepbound—have slipped to roughly $500 a month for people without insurance, several hundred dollars below their initial launch levels. Yet steady access remains elusive. Employers wary of rising drug bills have been slow to add the medicines to benefit plans, and most Medicaid programs and Medicare still refuse to cover them for weight-loss alone.
Read more
5 posts • OpenAI (o3)
Published
The UK’s Advertising Standards Authority has banned nine digital adverts that promoted prescription-only weight-loss injections to the public, ruling they breached national advertising codes. The decision covers a January Instagram video by television personality Gemma Collins, which endorsed Swedish digital healthcare provider Yazen’s weight-loss programme combining an app with medication. The ASA said the post, along with eight paid-for online ads from clinics and pharmacies, amounted to unlawful promotion of prescription medicines.
Read more
An Instagram post by TV personality Gemma Collins which advertised a weight-loss drug and app has been banned. It is illegal to advertise prescription-only weight loss drugs and Ms Collins' was one of nine adverts banned in a crackdown by the Advertising Standards Authority.
Weight loss jab adverts banned by watchdog
Gemma Collins weight-loss drug advert banned as watchdog launches crackdown
Gemma Collins weight-loss drug advert banned
Skinny jabs: Gemma Collins weight-loss advert banned as watchdog cracks down on rule-breakers
7 posts • GPT (4.1 mini)
Published
Recent studies and developments indicate that obesity treatments like semaglutide, marketed under names such as Ozempic, are paving the way for a new era in weight loss care. Novo Nordisk has submitted a new product dose to the European Medicines Agency, with clinical trials showing that one in three participants achieved at least 25% weight loss. Experts highlight that these GLP-1 receptor agonist drugs not only reduce appetite but also help address addictive behaviors related to ultra-processed foods. Former FDA commissioner David Kessler has noted the role of such medications in mitigating food addiction. Meanwhile, the FDA has accepted a New Drug Application for ET-600, an oral desmopressin solution by Eton Pharmaceuticals, with a Prescription Drug User Fee Act (PDUFA) date set for February 25, 2026.
38 posts • GPT (4.1 mini)
Published
Singer Lizzo has publicly addressed her recent weight loss journey, admitting that she tried the weight loss drug Ozempic and other GLP-1 medications but ultimately decided they were not the most effective method for her. She stated that Ozempic made her feel full, but she stopped using it, describing it as "not her way" to lose weight. Instead, Lizzo credits a high-protein, low-carbohydrate diet, including reintroducing meat after a previous vegan diet, as the key factor in her transformation. Since January 2023, she has lowered her body mass index (BMI) by 10.5 points and lost 16% of her body fat.
Lizzo also shared details of her regimen involving exercise, healthy eating, wood therapy, and lymphatic massages. She posted before-and-after photos on Instagram to highlight her progress and emphasized that her weight loss was achieved without relying on medication or surgery. The singer has sought to clarify rumors and speculation about her use of Ozempic, stressing the importance of a holistic approach to her health and fitness.
19 posts • GPT (4.1 mini)
Published
Novo Nordisk's experimental obesity drug demonstrated up to 24% weight loss in a small study, highlighting its potential as a next-generation treatment in the competitive obesity drug market. Eli Lilly's orforglipron, set for a 2026 launch, is also expected to reshape the market, with Citi projecting over $40 billion in sales by 2030, surpassing Bloomberg consensus estimates. Both Novo Nordisk and Eli Lilly, dominant players globally, now face emerging competition from China. Innovent Biologics recently received Chinese approval for its obesity drug mazdutide, which targets GLP-1R and GCGR receptors to increase energy expenditure, marking a significant step in China's efforts to address obesity and diabetes through local innovation.
Additionally, Syntes Bio, a startup founded by Bob Langer, has raised $33 million in Series A funding and plans to enter clinical trials this year. Despite these advances, Novo Nordisk reportedly misread the US market for its weight loss drug Wegovy, with internal warnings about insufficient launch preparedness. The obesity treatment landscape is evolving rapidly, with new oral alternatives also emerging to challenge established therapies like Ozempic.
12 posts • OpenAI (o3)
Published
Scientists at the Buck Institute for Research on Aging report that re-activating the enzyme glycogen phosphorylase (GlyP) in neurons curbs toxic tau protein build-up and oxidative stress, hallmarks of Alzheimer’s and related dementias. The peer-reviewed study, published 30 June in Nature Metabolism, shows that excessive glycogen accumulates in aging neurons because tau physically blocks its breakdown. Restoring GlyP activity in fruit-fly models and in human stem-cell-derived neurons diverted sugar molecules into the pentose phosphate pathway, raised protective antioxidants and lessened neurodegeneration.
The findings offer a biological explanation for why GLP-1 drugs—originally developed for diabetes and now widely prescribed for weight loss—appear to lower dementia risk in observational studies. GLP-1 treatment and dietary restriction both increased GlyP activity in the laboratory, mirroring the neuroprotective effects seen when the enzyme was switched back on directly.
Lead author Sudipta Bar said the work “opens a route to therapies that modulate the brain’s sugar economy,” while senior author Pankaj Kapahi added that targeting GlyP could complement ongoing drug and lifestyle strategies to slow cognitive decline. The team is now investigating whether newer GLP-1 compounds can replicate the results in larger animal models and, eventually, in clinical trials.
15 posts • OpenAI (o3)
Published
Nearly 98 million people in the United States aged 18 and over—about 38% of the adult population—have prediabetes, the Centers for Disease Control and Prevention estimates. Prediabetes is marked by blood-sugar levels higher than normal but below the threshold for Type 2 diabetes, leaving patients at elevated risk for the full disease and its cardiovascular and renal complications.
Type 2 diabetes represents 90–95% of all diabetes cases, yet public-health specialists note that up to 90% of those cases can be prevented or delayed through weight control, diet and exercise. The CDC urges adults who are overweight or obese and between 35 and 70 years old to undergo regular glucose screening and enroll in lifestyle-modification programs such as the National Diabetes Prevention Program.
Read more
With 20 million diabetics in Brazil and many without a diagnosis, obesity drives the increase of the disease, especially Type 2 Diabetes. Overweight impairs the action of insulin, a hormone that metabolizes glucose, fats, and proteins. Prediabetes, often
Type 2 diabetes affects up to 14% of the global population. This Review discusses the diagnosis, treatment, and prognosis of adults with type 2 diabetes. @ADA_DiabetesPro
When Type 2 diabetes is 90-95% of all diabetes cases AND Up to 90% of T2D can be prevented or delayed with lifestyle (diet and exercise) changes You’ve got to wonder why we aren’t prescribing / funding this more aggressively
Diabetes rates: 1. 🇵🇰 Pakistan: 30.8% 2. 🇰🇼 Kuwait: 24.9% 8. 🇪🇬 Egypt: 20.9% 10. 🇶🇦 Qatar: 19.5% 12. 🇲🇾 Malaysia: 19% 14. 🇸🇦 Saudi-Arabien: 18.7% 17. 🇲🇽 Mexiko: 16.9% 26. 🇹🇷 Turchia: 14.5% 27. 🇧🇩 Bangladesch: 14.2% 48. 🇱🇰 Sri Lanka: 11.3% 53. 🇿🇦 Afrique du Sud: 10.8% 54. 🇮🇶 Irak: 10.7% 55.
Nearly 98 million people in the United States over age 18 have prediabetes, according to the Centers for Disease Control and Prevention. That’s 38% of the U.S. adult population with higher-than-normal blood sugar levels.
5 posts • GPT (4.1 mini)
Published
Dr. Ambrish Mithal, a leading endocrinologist in India, has highlighted obesity as a critical health concern and a major contributor to modern non-communicable diseases. Nearly one in three Indians is obese, according to recent discussions involving Dr. Mithal and diabetologist Dr.
Rajiv Kovil. The Prime Minister has also addressed obesity as an important health red flag. Dr. Mithal emphasized that while new GLP-1 weight-loss drugs, such as Ozempic, are revolutionizing obesity treatment in India and showing promising benefits for conditions like Alzheimer's and cardiac diseases, lifestyle changes remain essential and cannot be replaced by medication alone. He noted that 9 out of 10 patients requiring surgery for obesity are unable to undergo the procedure, which is now reserved for severely obese individuals. Dr. Mithal also mentioned that non-diabetics are increasingly using Ozempic, and that weight loss is primarily linked to total calorie intake rather than intermittent fasting alone. He cautioned about potential side effects of weight loss drugs but stressed the importance of continuing diet and exercise as the cornerstone of treatment for obesity and related diseases. Dr. Mithal's book, "The Weight Loss Revolution," explores the science and solutions behind weight loss, addressing common questions about these new therapies.
19 posts • GPT (4.1 mini)
Published
Health authorities in the UK are investigating reports linking weight loss and diabetes injections, including Mounjaro, Wegovy, and Ozempic, to cases of pancreatitis. The Medicines and Healthcare Regulatory Agency (MHRA) has received nearly 300 reports of pancreatitis and at least 10 deaths potentially associated with these drugs, which have been used by over one million people in the country. The reported cases include both acute and chronic pancreatitis, prompting a new study involving the MHRA and Genomics England to examine the potential serious side effects. The investigation follows concerns that online pharmacies are bypassing general practitioners, leading to increased use of these injections. The UK regulator is continuing to monitor adverse events as the drugs remain widely used for weight loss and diabetes management.
5 posts • OpenAI (o3)
Published
Novo Nordisk executives used this week’s American Diabetes Association meeting in Chicago to rebut criticism that the Danish drugmaker has ceded leadership in the booming market for obesity treatments to Eli Lilly. Martin Lange, head of development, argued the company is deliberately pacing its research and commercial roll-outs, saying it is “playing the long game” rather than chasing the fastest headline weight-loss numbers.
The company highlighted late-stage candidates CagriSema—a combination of semaglutide and amylin analogue—and the dual-agonist amycretin, contending that ongoing studies have yet to show their full potential on weight reduction, tolerability and cardiometabolic benefits. Novo Nordisk is positioning the pipeline to give physicians a menu of options that balance efficacy, side-effect profiles and treatment goals such as diabetes control or liver-fat reduction, Lange said.
Novo’s more measured approach has drawn scrutiny as Lilly’s once-weekly tirzepatide gains market share and analysts note that Novo’s stock has fallen about 50% in the past 12 months. Company officials acknowledged past conservatism but said the strategy will yield durable growth when the next wave of data reads out.
7 posts • GPT (4.1 mini)
Published
Spain's Ministry of Health has launched an investigation into Novo Nordisk regarding a digital obesity awareness campaign that may have violated the country's laws prohibiting the promotion of prescription drugs. The probe focuses on whether the campaign constitutes indirect advertising of Novo Nordisk's weight-loss medications, including Wegovy and Ozempic. Authorities are scrutinizing the online campaign linked to Novo Nordisk to determine if it breaches advertising regulations. The investigation reflects growing regulatory attention on pharmaceutical marketing practices in Spain.
4 posts • OpenAI (o3)
Published
New data released Wednesday indicate that patient adherence to GLP-1 weight-loss injections remains relatively high during the first year of treatment but drops sharply over longer periods. About two-thirds of U.S. patients prescribed Novo Nordisk’s Wegovy or Eli Lilly’s Zepbound stayed on the medication for at least 12 months, according to the figures cited by multiple research outlets.
Long-term persistence is far lower: only one in seven Wegovy patients were still taking the drug after three years. Analysts said the pattern underscores the challenges of sustaining treatment amid cost, tolerability and insurance-coverage hurdles. The study also highlighted that perimenopausal women are a significant and growing share of new GLP-1 users, reflecting the drugs’ widening appeal beyond traditional obesity-management cohorts.
23 posts • GPT (4.1 mini)
Published
Danish pharmaceutical company Novo Nordisk has officially launched its blockbuster weight-loss drug Wegovy in India as a once-a-week injectable treatment. Wegovy is available in five dosage strengths: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg. The starting price for the lower doses (0.25 mg, 0.5 mg, and 1 mg) is approximately ₹17,345 per month (around $200), while the higher doses cost about $280 for 1.7 mg and $303 for 2.4 mg. Novo Nordisk plans to adjust pricing and accessibility based on local demand and competition, with further assessments expected after competitors enter the market in March 2026.
The launch comes months after US-based Eli Lilly introduced its weight-loss drug Mounjaro in India, which recently received regulatory approval for pre-filled injector pens to treat type 2 diabetes and obesity. Wegovy is noted as the first GLP-1 drug approved in India for both weight loss and cardiovascular risk reduction. India, which has the world's third-largest obese population, represents a key market for these treatments amid rising obesity rates. Novo Nordisk and Eli Lilly are positioned as primary competitors in the expanding Indian weight-loss drug market.
22 posts • GPT (4.1 mini)
Published
Danish pharmaceutical company Novo Nordisk has officially launched its blockbuster weight-loss drug Wegovy in India, offering it as a once-a-week injectable treatment. Wegovy is available in five dosage strengths: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg. Pricing for the lower three doses (0.25 mg, 0.5 mg, and 1 mg) is set at approximately ₹17,345 per month (around $200), while the higher doses are priced at $280 for 1.7 mg and about $303 for 2.4 mg. The launch comes months after US-based Eli Lilly introduced its competing weight-loss drug Mounjaro in India.
Novo Nordisk aims to tailor Wegovy's pricing to local demand and plans to reassess accessibility and pricing once competition intensifies in March 2026. Wegovy is noted as the first GLP-1 drug approved in India for both weight loss and cardiovascular risk reduction. Meanwhile, India's Central Drugs Standard Control Organization (CDSCO) has approved Eli Lilly's Mounjaro in a pre-filled injector pen format for treating type-2 diabetes and obesity, enhancing its market presence to compete with Wegovy. India, with the world's third-largest obese population, represents a critical market for both pharmaceutical companies as the weight-loss drug market heats up.
72 posts • OpenAI (o3)
Published
Novo Nordisk has terminated its less-than-two-month-old collaboration with telehealth provider Hims & Hers Health, alleging the U.S. company engaged in “illegal mass compounding” and “deceptive marketing” of copycat versions of its blockbuster obesity drug Wegovy. The move cuts Hims & Hers off from direct access to the FDA-approved therapy via NovoCare pharmacies.
The fallout sent Hims & Hers shares tumbling as much as 35 % on 23 June, their sharpest single-day decline on record, while Novo Nordisk slipped about 7 % in early trading. Needham downgraded HIMS to Hold and removed it from its conviction list, and Citi warned the dispute heightens legal and partnership risks, though it expects limited impact on the company’s 2025 earnings.
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18 posts • GPT (4.1 mini)
Published
Amanda Bynes has announced her plan to use the injectable weight loss medication Ozempic to lose over 40 pounds, aiming to reduce her weight from 173 pounds to approximately 130 pounds. The former Nickelodeon star cited her motivation as wanting to "look better in paparazzi pictures" following a series of invasive photos. Bynes has previously shared that weight gain was related to depression. Her decision to start Ozempic has drawn attention amid discussions of the drug's growing popularity in Hollywood and studies linking it to potential health benefits, including a lower risk of dementia. Bynes also recently joined OnlyFans, adding context to her public reemergence.
18 posts • GPT (4.1 mini)
Published
Novo Nordisk A/S has filed for an expansion of the Ozempic label in the United States, with a decision expected in the fourth quarter of 2025. The European Medicines Agency has adopted a positive opinion recommending the inclusion of peripheral artery disease on the Ozempic label, with the European Commission expected to finalize the update within two months. Ozempic, a semaglutide-based drug primarily used for type 2 diabetes, has demonstrated broader benefits for patients with comorbidities. Recent studies have shown that medications in the Ozempic family can reduce the frequency of chronic migraines, including those caused by medication overuse, potentially through mechanisms involving cerebrospinal fluid pressure reduction.
Additionally, emerging data from a nationwide population sample of 1.7 million people with diabetes suggest that semaglutide may reduce the risk of Alzheimer's disease and related dementias compared to other treatments such as insulin and metformin. Novo Nordisk is also conducting phase 3 trials with oral semaglutide (Rybelsus) targeting Alzheimer's disease, with results anticipated in the fourth quarter of 2025. These findings highlight the expanding therapeutic potential of semaglutide beyond diabetes management.
12 posts • OpenAI (o3)
Published
Amanda Bynes said in an Instagram video posted over the weekend that she will begin using Ozempic, the diabetes drug increasingly prescribed off-label for weight management, to reduce her weight from 173 pounds to about 130. “I’m going on Ozempic … so I look better in paparazzi pictures,” the former Nickelodeon star told followers, pledging to share updates on what she called her “Ozempic journey.”
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22 posts • GPT (4.1 mini)
Published
Singer Lizzo has publicly acknowledged trying the weight loss drug Ozempic, as well as other GLP-1 medications, during her recent weight loss journey. She initially denied using such drugs amid rumors but later confirmed she experimented with them before deciding they were not the most effective method for her. Lizzo stated that Ozempic made her feel full and helped reduce her appetite, but ultimately she stopped using the drug, describing it as "not her way" to lose weight. Instead, she credited a dietary change—specifically ditching fake meat—as the key factor behind her successful weight loss. Lizzo emphasized a "mind over matter" approach and revealed that this diet adjustment had a more significant impact on her transformation than medication. She has been open about trying various methods to achieve her weight loss goals and continues to share her journey with fans.
5 posts • OpenAI (o3)
Published
Nearly one-third of U.S. adolescents aged 12 to 17—about 8.4 million youths—had prediabetes in 2023, according to new data from the Centers for Disease Control and Prevention. The analysis of fasting blood-glucose and hemoglobin A1c tests from the National Health and Nutrition Examination Survey found a prevalence rate of 32.7%, indicating blood-sugar levels that are elevated but not yet in the diabetic range.
Read more
When my uncle was president, childhood diabetes was almost unheard of. Now, 1 in 3 kids is diabetic or pre-diabetic. We understand what’s driving this epidemic, and we have the power to stop it. It begins with what we eat. It’s time to take back our children’s health and Make
33% of Americans between 12 and 17 are pre-diabetic, according to CDC statistics. Follow: @AFpost
An estimated 1 in 3 teens and preteens, ages 12 to 17, have prediabetes, according to new data from the CDC.
Nearly 1 in 3 American adolescents have prediabetes, a CDC report finds. An official notes "it’s not too late to change course."
1/3rd of US teens (>8 million kids) have prediabetes
11 posts • OpenAI (o3)
Published
Prices for the two leading obesity injections—Novo Nordisk’s semaglutide shot Wegovy and Eli Lilly’s tirzepatide shot Zepbound—have slipped to roughly $500 a month for people without insurance, several hundred dollars below their initial launch levels. Yet steady access remains elusive. Employers wary of rising drug bills have been slow to add the medicines to benefit plans, and most Medicaid programs and Medicare still refuse to cover them for weight-loss alone.
Read more
5 posts • OpenAI (o3)
Published
The UK’s Advertising Standards Authority has banned nine digital adverts that promoted prescription-only weight-loss injections to the public, ruling they breached national advertising codes. The decision covers a January Instagram video by television personality Gemma Collins, which endorsed Swedish digital healthcare provider Yazen’s weight-loss programme combining an app with medication. The ASA said the post, along with eight paid-for online ads from clinics and pharmacies, amounted to unlawful promotion of prescription medicines.
Read more
An Instagram post by TV personality Gemma Collins which advertised a weight-loss drug and app has been banned. It is illegal to advertise prescription-only weight loss drugs and Ms Collins' was one of nine adverts banned in a crackdown by the Advertising Standards Authority.
Weight loss jab adverts banned by watchdog
Gemma Collins weight-loss drug advert banned as watchdog launches crackdown
Gemma Collins weight-loss drug advert banned
Skinny jabs: Gemma Collins weight-loss advert banned as watchdog cracks down on rule-breakers
7 posts • GPT (4.1 mini)
Published
Recent studies and developments indicate that obesity treatments like semaglutide, marketed under names such as Ozempic, are paving the way for a new era in weight loss care. Novo Nordisk has submitted a new product dose to the European Medicines Agency, with clinical trials showing that one in three participants achieved at least 25% weight loss. Experts highlight that these GLP-1 receptor agonist drugs not only reduce appetite but also help address addictive behaviors related to ultra-processed foods. Former FDA commissioner David Kessler has noted the role of such medications in mitigating food addiction. Meanwhile, the FDA has accepted a New Drug Application for ET-600, an oral desmopressin solution by Eton Pharmaceuticals, with a Prescription Drug User Fee Act (PDUFA) date set for February 25, 2026.
38 posts • GPT (4.1 mini)
Published
Singer Lizzo has publicly addressed her recent weight loss journey, admitting that she tried the weight loss drug Ozempic and other GLP-1 medications but ultimately decided they were not the most effective method for her. She stated that Ozempic made her feel full, but she stopped using it, describing it as "not her way" to lose weight. Instead, Lizzo credits a high-protein, low-carbohydrate diet, including reintroducing meat after a previous vegan diet, as the key factor in her transformation. Since January 2023, she has lowered her body mass index (BMI) by 10.5 points and lost 16% of her body fat.
Lizzo also shared details of her regimen involving exercise, healthy eating, wood therapy, and lymphatic massages. She posted before-and-after photos on Instagram to highlight her progress and emphasized that her weight loss was achieved without relying on medication or surgery. The singer has sought to clarify rumors and speculation about her use of Ozempic, stressing the importance of a holistic approach to her health and fitness.
19 posts • GPT (4.1 mini)
Published
Novo Nordisk's experimental obesity drug demonstrated up to 24% weight loss in a small study, highlighting its potential as a next-generation treatment in the competitive obesity drug market. Eli Lilly's orforglipron, set for a 2026 launch, is also expected to reshape the market, with Citi projecting over $40 billion in sales by 2030, surpassing Bloomberg consensus estimates. Both Novo Nordisk and Eli Lilly, dominant players globally, now face emerging competition from China. Innovent Biologics recently received Chinese approval for its obesity drug mazdutide, which targets GLP-1R and GCGR receptors to increase energy expenditure, marking a significant step in China's efforts to address obesity and diabetes through local innovation.
Additionally, Syntes Bio, a startup founded by Bob Langer, has raised $33 million in Series A funding and plans to enter clinical trials this year. Despite these advances, Novo Nordisk reportedly misread the US market for its weight loss drug Wegovy, with internal warnings about insufficient launch preparedness. The obesity treatment landscape is evolving rapidly, with new oral alternatives also emerging to challenge established therapies like Ozempic.
12 posts • OpenAI (o3)
Published
Scientists at the Buck Institute for Research on Aging report that re-activating the enzyme glycogen phosphorylase (GlyP) in neurons curbs toxic tau protein build-up and oxidative stress, hallmarks of Alzheimer’s and related dementias. The peer-reviewed study, published 30 June in Nature Metabolism, shows that excessive glycogen accumulates in aging neurons because tau physically blocks its breakdown. Restoring GlyP activity in fruit-fly models and in human stem-cell-derived neurons diverted sugar molecules into the pentose phosphate pathway, raised protective antioxidants and lessened neurodegeneration.
The findings offer a biological explanation for why GLP-1 drugs—originally developed for diabetes and now widely prescribed for weight loss—appear to lower dementia risk in observational studies. GLP-1 treatment and dietary restriction both increased GlyP activity in the laboratory, mirroring the neuroprotective effects seen when the enzyme was switched back on directly.
Lead author Sudipta Bar said the work “opens a route to therapies that modulate the brain’s sugar economy,” while senior author Pankaj Kapahi added that targeting GlyP could complement ongoing drug and lifestyle strategies to slow cognitive decline. The team is now investigating whether newer GLP-1 compounds can replicate the results in larger animal models and, eventually, in clinical trials.
15 posts • OpenAI (o3)
Published
Nearly 98 million people in the United States aged 18 and over—about 38% of the adult population—have prediabetes, the Centers for Disease Control and Prevention estimates. Prediabetes is marked by blood-sugar levels higher than normal but below the threshold for Type 2 diabetes, leaving patients at elevated risk for the full disease and its cardiovascular and renal complications.
Type 2 diabetes represents 90–95% of all diabetes cases, yet public-health specialists note that up to 90% of those cases can be prevented or delayed through weight control, diet and exercise. The CDC urges adults who are overweight or obese and between 35 and 70 years old to undergo regular glucose screening and enroll in lifestyle-modification programs such as the National Diabetes Prevention Program.
Read more
With 20 million diabetics in Brazil and many without a diagnosis, obesity drives the increase of the disease, especially Type 2 Diabetes. Overweight impairs the action of insulin, a hormone that metabolizes glucose, fats, and proteins. Prediabetes, often
Type 2 diabetes affects up to 14% of the global population. This Review discusses the diagnosis, treatment, and prognosis of adults with type 2 diabetes. @ADA_DiabetesPro
When Type 2 diabetes is 90-95% of all diabetes cases AND Up to 90% of T2D can be prevented or delayed with lifestyle (diet and exercise) changes You’ve got to wonder why we aren’t prescribing / funding this more aggressively
Diabetes rates: 1. 🇵🇰 Pakistan: 30.8% 2. 🇰🇼 Kuwait: 24.9% 8. 🇪🇬 Egypt: 20.9% 10. 🇶🇦 Qatar: 19.5% 12. 🇲🇾 Malaysia: 19% 14. 🇸🇦 Saudi-Arabien: 18.7% 17. 🇲🇽 Mexiko: 16.9% 26. 🇹🇷 Turchia: 14.5% 27. 🇧🇩 Bangladesch: 14.2% 48. 🇱🇰 Sri Lanka: 11.3% 53. 🇿🇦 Afrique du Sud: 10.8% 54. 🇮🇶 Irak: 10.7% 55.
Nearly 98 million people in the United States over age 18 have prediabetes, according to the Centers for Disease Control and Prevention. That’s 38% of the U.S. adult population with higher-than-normal blood sugar levels.
5 posts • GPT (4.1 mini)
Published
Dr. Ambrish Mithal, a leading endocrinologist in India, has highlighted obesity as a critical health concern and a major contributor to modern non-communicable diseases. Nearly one in three Indians is obese, according to recent discussions involving Dr. Mithal and diabetologist Dr.
Rajiv Kovil. The Prime Minister has also addressed obesity as an important health red flag. Dr. Mithal emphasized that while new GLP-1 weight-loss drugs, such as Ozempic, are revolutionizing obesity treatment in India and showing promising benefits for conditions like Alzheimer's and cardiac diseases, lifestyle changes remain essential and cannot be replaced by medication alone. He noted that 9 out of 10 patients requiring surgery for obesity are unable to undergo the procedure, which is now reserved for severely obese individuals. Dr. Mithal also mentioned that non-diabetics are increasingly using Ozempic, and that weight loss is primarily linked to total calorie intake rather than intermittent fasting alone. He cautioned about potential side effects of weight loss drugs but stressed the importance of continuing diet and exercise as the cornerstone of treatment for obesity and related diseases. Dr. Mithal's book, "The Weight Loss Revolution," explores the science and solutions behind weight loss, addressing common questions about these new therapies.
19 posts • GPT (4.1 mini)
Published
Health authorities in the UK are investigating reports linking weight loss and diabetes injections, including Mounjaro, Wegovy, and Ozempic, to cases of pancreatitis. The Medicines and Healthcare Regulatory Agency (MHRA) has received nearly 300 reports of pancreatitis and at least 10 deaths potentially associated with these drugs, which have been used by over one million people in the country. The reported cases include both acute and chronic pancreatitis, prompting a new study involving the MHRA and Genomics England to examine the potential serious side effects. The investigation follows concerns that online pharmacies are bypassing general practitioners, leading to increased use of these injections. The UK regulator is continuing to monitor adverse events as the drugs remain widely used for weight loss and diabetes management.
5 posts • OpenAI (o3)
Published
Novo Nordisk executives used this week’s American Diabetes Association meeting in Chicago to rebut criticism that the Danish drugmaker has ceded leadership in the booming market for obesity treatments to Eli Lilly. Martin Lange, head of development, argued the company is deliberately pacing its research and commercial roll-outs, saying it is “playing the long game” rather than chasing the fastest headline weight-loss numbers.
The company highlighted late-stage candidates CagriSema—a combination of semaglutide and amylin analogue—and the dual-agonist amycretin, contending that ongoing studies have yet to show their full potential on weight reduction, tolerability and cardiometabolic benefits. Novo Nordisk is positioning the pipeline to give physicians a menu of options that balance efficacy, side-effect profiles and treatment goals such as diabetes control or liver-fat reduction, Lange said.
Novo’s more measured approach has drawn scrutiny as Lilly’s once-weekly tirzepatide gains market share and analysts note that Novo’s stock has fallen about 50% in the past 12 months. Company officials acknowledged past conservatism but said the strategy will yield durable growth when the next wave of data reads out.
7 posts • GPT (4.1 mini)
Published
Spain's Ministry of Health has launched an investigation into Novo Nordisk regarding a digital obesity awareness campaign that may have violated the country's laws prohibiting the promotion of prescription drugs. The probe focuses on whether the campaign constitutes indirect advertising of Novo Nordisk's weight-loss medications, including Wegovy and Ozempic. Authorities are scrutinizing the online campaign linked to Novo Nordisk to determine if it breaches advertising regulations. The investigation reflects growing regulatory attention on pharmaceutical marketing practices in Spain.
4 posts • OpenAI (o3)
Published
New data released Wednesday indicate that patient adherence to GLP-1 weight-loss injections remains relatively high during the first year of treatment but drops sharply over longer periods. About two-thirds of U.S. patients prescribed Novo Nordisk’s Wegovy or Eli Lilly’s Zepbound stayed on the medication for at least 12 months, according to the figures cited by multiple research outlets.
Long-term persistence is far lower: only one in seven Wegovy patients were still taking the drug after three years. Analysts said the pattern underscores the challenges of sustaining treatment amid cost, tolerability and insurance-coverage hurdles. The study also highlighted that perimenopausal women are a significant and growing share of new GLP-1 users, reflecting the drugs’ widening appeal beyond traditional obesity-management cohorts.
23 posts • GPT (4.1 mini)
Published
Danish pharmaceutical company Novo Nordisk has officially launched its blockbuster weight-loss drug Wegovy in India as a once-a-week injectable treatment. Wegovy is available in five dosage strengths: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg. The starting price for the lower doses (0.25 mg, 0.5 mg, and 1 mg) is approximately ₹17,345 per month (around $200), while the higher doses cost about $280 for 1.7 mg and $303 for 2.4 mg. Novo Nordisk plans to adjust pricing and accessibility based on local demand and competition, with further assessments expected after competitors enter the market in March 2026.
The launch comes months after US-based Eli Lilly introduced its weight-loss drug Mounjaro in India, which recently received regulatory approval for pre-filled injector pens to treat type 2 diabetes and obesity. Wegovy is noted as the first GLP-1 drug approved in India for both weight loss and cardiovascular risk reduction. India, which has the world's third-largest obese population, represents a key market for these treatments amid rising obesity rates. Novo Nordisk and Eli Lilly are positioned as primary competitors in the expanding Indian weight-loss drug market.
22 posts • GPT (4.1 mini)
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Danish pharmaceutical company Novo Nordisk has officially launched its blockbuster weight-loss drug Wegovy in India, offering it as a once-a-week injectable treatment. Wegovy is available in five dosage strengths: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg. Pricing for the lower three doses (0.25 mg, 0.5 mg, and 1 mg) is set at approximately ₹17,345 per month (around $200), while the higher doses are priced at $280 for 1.7 mg and about $303 for 2.4 mg. The launch comes months after US-based Eli Lilly introduced its competing weight-loss drug Mounjaro in India.
Novo Nordisk aims to tailor Wegovy's pricing to local demand and plans to reassess accessibility and pricing once competition intensifies in March 2026. Wegovy is noted as the first GLP-1 drug approved in India for both weight loss and cardiovascular risk reduction. Meanwhile, India's Central Drugs Standard Control Organization (CDSCO) has approved Eli Lilly's Mounjaro in a pre-filled injector pen format for treating type-2 diabetes and obesity, enhancing its market presence to compete with Wegovy. India, with the world's third-largest obese population, represents a critical market for both pharmaceutical companies as the weight-loss drug market heats up.
72 posts • OpenAI (o3)
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Novo Nordisk has terminated its less-than-two-month-old collaboration with telehealth provider Hims & Hers Health, alleging the U.S. company engaged in “illegal mass compounding” and “deceptive marketing” of copycat versions of its blockbuster obesity drug Wegovy. The move cuts Hims & Hers off from direct access to the FDA-approved therapy via NovoCare pharmacies.
The fallout sent Hims & Hers shares tumbling as much as 35 % on 23 June, their sharpest single-day decline on record, while Novo Nordisk slipped about 7 % in early trading. Needham downgraded HIMS to Hold and removed it from its conviction list, and Citi warned the dispute heightens legal and partnership risks, though it expects limited impact on the company’s 2025 earnings.
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Amanda Bynes has announced her plan to use the injectable weight loss medication Ozempic to lose over 40 pounds, aiming to reduce her weight from 173 pounds to approximately 130 pounds. The former Nickelodeon star cited her motivation as wanting to "look better in paparazzi pictures" following a series of invasive photos. Bynes has previously shared that weight gain was related to depression. Her decision to start Ozempic has drawn attention amid discussions of the drug's growing popularity in Hollywood and studies linking it to potential health benefits, including a lower risk of dementia. Bynes also recently joined OnlyFans, adding context to her public reemergence.
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Novo Nordisk A/S has filed for an expansion of the Ozempic label in the United States, with a decision expected in the fourth quarter of 2025. The European Medicines Agency has adopted a positive opinion recommending the inclusion of peripheral artery disease on the Ozempic label, with the European Commission expected to finalize the update within two months. Ozempic, a semaglutide-based drug primarily used for type 2 diabetes, has demonstrated broader benefits for patients with comorbidities. Recent studies have shown that medications in the Ozempic family can reduce the frequency of chronic migraines, including those caused by medication overuse, potentially through mechanisms involving cerebrospinal fluid pressure reduction.
Additionally, emerging data from a nationwide population sample of 1.7 million people with diabetes suggest that semaglutide may reduce the risk of Alzheimer's disease and related dementias compared to other treatments such as insulin and metformin. Novo Nordisk is also conducting phase 3 trials with oral semaglutide (Rybelsus) targeting Alzheimer's disease, with results anticipated in the fourth quarter of 2025. These findings highlight the expanding therapeutic potential of semaglutide beyond diabetes management.
12 posts • OpenAI (o3)
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Amanda Bynes said in an Instagram video posted over the weekend that she will begin using Ozempic, the diabetes drug increasingly prescribed off-label for weight management, to reduce her weight from 173 pounds to about 130. “I’m going on Ozempic … so I look better in paparazzi pictures,” the former Nickelodeon star told followers, pledging to share updates on what she called her “Ozempic journey.”
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Singer Lizzo has publicly acknowledged trying the weight loss drug Ozempic, as well as other GLP-1 medications, during her recent weight loss journey. She initially denied using such drugs amid rumors but later confirmed she experimented with them before deciding they were not the most effective method for her. Lizzo stated that Ozempic made her feel full and helped reduce her appetite, but ultimately she stopped using the drug, describing it as "not her way" to lose weight. Instead, she credited a dietary change—specifically ditching fake meat—as the key factor behind her successful weight loss. Lizzo emphasized a "mind over matter" approach and revealed that this diet adjustment had a more significant impact on her transformation than medication. She has been open about trying various methods to achieve her weight loss goals and continues to share her journey with fans.
