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DNA vaccines, which are easier to store than mRNA alternatives, could be tested in people next year for infections such as yellow fever. The FDA will evaluate the first self-administered FluMist vaccine. Childhood vaccine exemptions have reached the highest level ever, increasing the risk of outbreaks of polio, measles, and more. The percentage of kindergarteners whose parents opted them out of school-required vaccinations rose to the highest level during the 2022-2023 school year. The first vaccine against chikungunya may soon come to market and is expected to be recommended to U.S. travelers first. Additionally, the first vaccine approved to fight malaria has cut deaths among young children by 13% over nearly 4 years in Africa. The world's first recombinant anthrax vaccine seeks approval to prepare against potential bioterrorism.