The world's first human trial of a drug designed to regenerate teeth is set to begin in September 2024 in Japan. The groundbreaking trial will be conducted at Kyoto University Hospital and will involve 30 male participants aged 30-64 who are missing at least one molar. The drug, which blocks the USAG-1 protein that suppresses tooth growth, has shown promising results in animal trials with no significant side effects in ferrets and mice. If successful, the treatment could be commercially available by 2030. The initial phase of the trial will last 11 months, after which researchers plan to extend the study to include children aged 2-7 with congenital tooth deficiency and individuals with partial edentulism. "We want to do something to help those who are suffering from tooth loss or absence," said lead researcher Katsu Takahashi, head of dentistry and oral surgery at Kitano Hospital in Osaka, Japan.
According to Yahoo, the world's first human trial of a drug that can regenerate teeth will begin in a few months, less than a year on from news of its success in animals. This paves the way for the medicine to be commercially available as early as 2030. Would yall do it if… https://t.co/voWEUcEysb
The world's first human trial of a drug that can regenerate teeth will begin in a few months https://t.co/nqMFQQ1HKQ
🦷 World's first tooth-regenerating drug to enter testing in Japan “Startup aims to roll out antibody treatment in 2030 as alternative to implants” I knew this had to come from Kyoto! 🇯🇵 https://t.co/NULYjV4MRm https://t.co/gK2eM2gsBP https://t.co/OzStrUdmNh https://t.co/eSq8MiKSYM
Scientists say they're close to a breakthrough drug that can regenerate human teeth 🦷 • Successful in animal trials • Human trials start in a few months • Aim is for commercial availability by 2030 https://t.co/ZOhutQRYQt
🚨NEW DRUG TO REGROW TEETH ENTERS HUMAN TRIALS Japanese researchers developed a drug to regrow teeth, set to begin human trials in September. The drug blocks the USAG-1 protein, which suppresses tooth growth. Initial trials will involve adults missing a molar, followed by… https://t.co/FV2O2ZyboU
Funny thing with how patients speak before I look at them: “I have severely receding gums, I’m grinding my teeth, might have 3 cavities, and I haven’t worn my retainer” > perfect teeth “I floss 7 times a day, and brush after every meal, do we really need X-rays?” > disaster
The research team also aims to broaden the scope of the trial to include individuals with partial edentulism, characterized by the loss of one to five permanent teeth due to environmental factors. https://t.co/3RoxPo6odG
Japan is set to conduct clinical trials for the first "tooth regrowth medicine" starting in September 2024. The trials will involve testing the drug's ability to regrow teeth on 30 adult males. 🦷 https://t.co/oC2FIWYp3O
Following the initial 11-month phase, researchers plan to extend the trial to children ages 2-7 who suffer from congenital tooth deficiency, which results in the absence of multiple teeth. https://t.co/3RoxPo6W3e
The efficacy of the intravenous treatment for human teeth regeneration will be assessed, building on its successful application in ferrets and mice, which showed no significant side effects. https://t.co/3RoxPo6W3e
"While there has been no treatment to date providing a permanent cure, we feel that people's expectations for tooth growth are high." https://t.co/3RoxPo6W3e
"We want to do something to help those who are suffering from tooth loss or absence," said lead researcher Katsu Takahashi, head of dentistry and oral surgery at Kitano Hospital in Osaka, Japan, New Atlas reported. https://t.co/3RoxPo6W3e
Scheduled to take place at Japan's Kyoto University Hospital, the trial will run from September through August 2025 and will involve 30 male participants ages 30-64 who are missing at least one molar. https://t.co/3RoxPo6W3e
1/n Big news: the first human trial of a med that can regenerate teeth begins in a few months, less than a year after success in animals. The med may be commercially available as early as 2030. #Dentistry, #teeth: https://t.co/z4NCECKT5a
World's 1st 'tooth regrowth medicine' to be tested in Japan from Sept. 2024 https://t.co/eeQ3rOrsTS
Groundbreaking human trial for tooth regeneration drug set to begin https://t.co/XCFJSZ8Dzw https://t.co/ZmVtvzoP0N
The world's first clinical trial of a drug designed to regenerate human teeth is slated to start in a few months, following promising results from animal studies. If successful, the revolutionary treatment could be available commercially by 2030. https://t.co/JacXhuFg0A
The world’s first tooth-regrowing drug has been approved for human trials https://t.co/UwTmc4rEIS
Groundbreaking human trial for tooth regeneration drug set to begin - https://t.co/aUkYUYo1Ju
Japanese scientists propose drug to regrow teeth, promise trials won't bite https://t.co/ZHvY5vQ7X3
An intravenous treatment that can regenerate teeth? That would be a game-changer! I shared the news about the successful animal trials many months ago and now it seems the Kyoto University Hospital will launch a clinical trial with human patients in 2025. https://t.co/65vo9WFXDp
World-first tooth-regrowing drug will be given to humans in September https://t.co/9he8jyT4vi
World-first tooth-regrowing drug will be given to humans in September The world's first human trial of a drug that can regenerate teeth will begin in a few months, less than a year on from news of its success in animals. This paves the way for the medicine to be commercially… https://t.co/gmbilrqJeJ