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Ozempic Weight Loss Drug Linked to 'Ozempic Feet' Side Effect Amid 500% Spending Rise and New Oral GLP-1 Pills

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Updated Apr 22, 2025, 04:53 AM

The weight loss drug Ozempic, a GLP-1 receptor agonist, has gained celebrity popularity but is associated with a newly observed side effect termed "Ozempic feet," characterized by sagging, veiny skin on the feet that appears aged. While some attribute this to the drug, others argue it results from weight loss and cosmetic procedures rather than the medication itself. GLP-1 drugs like Ozempic and Wegovy have seen a 500 percent increase in spending over five years, reflecting their growing use for obesity and Type 2 diabetes treatment. Research indicates these medications effectively reduce fat mass more than muscle mass, improving metabolic health and lowering risks for heart attack, dementia, and inflammation.

New oral GLP-1 pills are emerging as alternatives to injectable forms, potentially offering similar benefits with fewer side effects. Despite their efficacy, concerns remain about access, side effects, and the need for more research, especially regarding gender-specific responses. Additionally, GLP-1 therapies show promise in treating rare conditions such as Bardet-Biedl Syndrome. The widespread adoption of these drugs has also impacted the global economy, with an estimated $12 billion loss in the snack market due to reduced consumption. Experts emphasize maintaining healthy lifestyle habits alongside medical treatments for longevity and healthspan extension.

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#Ozempic #Wegovy

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Sources

insideprecisionmedicine.com nytimes.com elmundo.es longevity.technology

HKU Public Health

@HKU_SPH

【Latest Research】#HKUSPH latest research reveals genetic evidence that diabetes medications, GLP-1 receptor agonists, reduce weight by decreasing more fat mass than muscle mass. 📉 For each unit reduction in BMI: · Whole-body fat mass ⬇️7.9 kg · Muscle mass ⬇️6.4 kg · Overall https://t.co/mOYACUAgZI

Inside Precision Medicine

@Inside_PM

GLP-1 Drugs Show Potential as Treatment for Bardet-Biedl Syndrome GLP-1 therapies significantly improved metabolic function, reduced food intake, and helped normalize hormone levels in BBS mouse models. #Monell @ucl @Penn @UF https://t.co/5irSVPSEdi

Jeet Sidhu

@jeetsidhu_

The biggest constrainst on lifespan in America are lifestyle factors like no exercise and alcohol/drug use. AI will not save you. https://t.co/xdF5s6r7Co

Story Timeline

2 months ago•Latest version

Ozempic Weight Loss Drug Linked to 'Ozempic Feet' Side Effect Amid 500% Spending Rise and New Oral GLP-1 Pills

2 months ago

Ozempic and Mounjaro Use Rises Globally With Ozempic Feet Side Effect, Anvisa Mandates Prescription, and Daily Pill Breakthrough

2 months ago•Original version

Study Links GLP-1 Agonists Like Ozempic to Depression Risk Amid Canadian Guidelines, Telehealth Concerns, and Rising Demand

Ozempic Weight Loss Drug Linked to 'Ozempic Feet' Side Effect Amid 500% Spending Rise and New Oral GLP-1 Pills

Related Prediction Markets

Trump confirmed taking Ozempic before July?

Sources

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