Recent discussions on Twitter among health and fitness enthusiasts have highlighted a study suggesting that resistance training induces the release of extracellular vesicles from muscles, which then communicate with fat cells to promote lipolysis, potentially offering a new perspective on fat loss beyond the traditional Calories In, Calories Out (CICO) model. This mechanism involves the transfer of micro RNA and DNA from muscles to fat cells, altering their metabolism. The study, described as showing muscles acting as endocrine organs, adds to the growing evidence that exercise, including both resistance training and aerobic exercise, plays a significant role in metabolic health and interorgan communication. Furthermore, the study's findings, titled "Mechanical overload‐induced muscle‐derived extracellular vesicles promote adipose tissue lipolysis," suggest a direct link between specific types of physical activity and metabolic changes. Discussions also touched on the potential benefits of aerobic exercise in addressing metabolic changes caused by methamphetamine addiction and its neuroprotective nature in managing Parkinson’s disease symptoms. A comparison between resistance training (RT) and aerobic endurance training (AET) highlighted RT's advantages in affecting key metabolic parameters.
"There is a growing body of evidence that extracellular vesicles (EVs) and their cargo of RNA, DNA, and protein are released in the circulation with exercise and might mediate interorgan communication" this is wild https://t.co/W5ltkvJ61P
Resistance training(RT) vs aerobic endurance training (AET) effects on key metabolic parameters. Both have benefits but RT seems to have the advantage in this study. https://t.co/TEwYnP7Vlr https://t.co/6ie7c7n1M8
Methamphetamine addiction can result in changes in brain energy metabolism. Aerobic exercise might be able to address some of these changes and restore metabolic health... at least in mice. https://t.co/papbnQeg1I
The neuroprotective nature of aerobic exercise influences a variety of Parkinson’s disease symptoms, on top of its role in impacting disease risk and progression. https://t.co/v7NjQTkZfV
Mechanical overload‐induced muscle‐derived extracellular vesicles promote adipose tissue lipolysis https://t.co/uYLx4judu5
Hypertrophic overload causes the muscles to release messenger vesicles with micro DNA, which is then received by adipose tissue and then causes lipolysis does this mean resistance training can cause fat loss outside of the CICO model? this is above my pay grade. I need back up:… https://t.co/kQ90TRD8FB
in short: exercise causes muscles to release little extra cellular vesicles that contain micro rna which change the metabolism of recipient cells. muscle as endocrine organs in other words https://t.co/UGqm73dAmz
lifting weights creates little messengers (extra cellular vesicles) that swim from the muscles to the fat and tells the fat to go away that’s my layman’s reading of this study here @DrDeepMD can you translate this study below into something us regular people can understand ? https://t.co/JbMiK0Q9m9