Recent studies have highlighted the significant impact of exercise on cellular and metabolic processes, with a particular focus on the role of extracellular vesicles (EVs) in mediating interorgan communication. These studies suggest that weight training and other forms of exercise induce the release of EVs from muscle cells, which then communicate with adipose tissue to promote lipolysis, the breakdown of fat cells, potentially challenging the Calories In, Calories Out (CICO) model. This process is facilitated by the transfer of micro RNA and possibly micro DNA within these vesicles, indicating a complex mechanism by which exercise influences metabolic health beyond simple calorie burning. Additionally, research points to the potential of exercise in addressing metabolic changes associated with methamphetamine addiction and Parkinson's disease, as well as its effectiveness as a treatment for depression, according to Australian research published in BMJ. The findings underscore the multifaceted benefits of exercise, particularly resistance training over aerobic endurance training (AET), in enhancing metabolic parameters and overall health.
I’ve gone down the rabbit hole of extra cellular vesicles which get sent from muscle mass to other organs and then change those cells metabolism. It’s like the muscle is an endocrine organ. it tells fat to unalive itself. lipolysis. I need to dig deeper and see if this…
"There is a growing body of evidence that extracellular vesicles (EVs) and their cargo of RNA, DNA, and protein are released in the circulation with exercise and might mediate interorgan communication" this is wild https://t.co/W5ltkvJ61P
Resistance training(RT) vs aerobic endurance training (AET) effects on key metabolic parameters. Both have benefits but RT seems to have the advantage in this study. https://t.co/TEwYnP7Vlr https://t.co/6ie7c7n1M8
SCIENCE: Exercise such as walking, jogging and strength training, particularly when intense, are 'an effective treatment for depression' and 'could be considered alongside psychotherapy and antidepressants as core treatments', according to Australian research published in BMJ.
Methamphetamine addiction can result in changes in brain energy metabolism. Aerobic exercise might be able to address some of these changes and restore metabolic health... at least in mice. https://t.co/papbnQeg1I
The neuroprotective nature of aerobic exercise influences a variety of Parkinson’s disease symptoms, on top of its role in impacting disease risk and progression. https://t.co/v7NjQTkZfV
Mechanical overload‐induced muscle‐derived extracellular vesicles promote adipose tissue lipolysis https://t.co/uYLx4judu5
Hypertrophic overload causes the muscles to release messenger vesicles with micro DNA, which is then received by adipose tissue and then causes lipolysis does this mean resistance training can cause fat loss outside of the CICO model? this is above my pay grade. I need back up:… https://t.co/kQ90TRD8FB
in short: exercise causes muscles to release little extra cellular vesicles that contain micro rna which change the metabolism of recipient cells. muscle as endocrine organs in other words https://t.co/UGqm73dAmz
lifting weights creates little messengers (extra cellular vesicles) that swim from the muscles to the fat and tells the fat to go away that’s my layman’s reading of this study here @DrDeepMD can you translate this study below into something us regular people can understand ? https://t.co/JbMiK0Q9m9
Current understanding of the role of Adipose-derived Extracellular Vesicles in Metabolic Homeostasis and Diseases: Communication from the distance between cells/tissues https://t.co/io1ZvPz4UH #Theranostics
Weight training induces lipolysis in fat cells… according to this study👇🏻 https://t.co/DstJQmMcgj