A new study has highlighted the potential of STK33, a protein essential for male fertility in humans and mice, as a target for nonhormonal and reversible male contraceptives. The study, sponsored by Promega and published in Science Magazine, demonstrated the effectiveness of CDD-2807, a tool compound that achieves reversible inhibition of spermatogenesis in mice. An injection that temporarily affects sperm movement has shown promise as a potential male contraceptive. The targeted inhibition of serine/threonine kinase 33 is central to this contraceptive method.
A new Science study in mice underscores the potential of STK33—a protein essential for male fertility in humans and mice—as a druggable target, offering a promising avenue for the development of nonhormonal and reversible male contraceptives. https://t.co/QjSAxkA6zZ https://t.co/FRaFjhVNzT
A novel, non-hormonal reversible contraceptive for men appears to be effective in mice, based on the results of a study sponsored by biological analysis company Promega. https://t.co/znzNrRcn0k
A promising approach to develop a birth control pill for men The world’s population has increased by more than 2.6-fold in the last 60 years. The growing trend continues – projections indicate that the number of people living on our planet will grow to 9 billion by 2037 from 8… https://t.co/VgRt5k85Mu
An injection that temporarily affects sperm movement has shown promise as a potential male contraceptive in mice. https://t.co/QO5HUP2tRo
Reversible male contraception by targeted inhibition of serine/threonine kinase 33 https://t.co/0iiXlAsVNY https://t.co/V4ZhVIxJhT
An injection that temporarily affects sperm movement has shown promise as a potential male contraceptive in mice e https://t.co/jlpwHQYccG
Towards male contraception. STK33 is a chemically validated, nonhormonal contraceptive target, and CDD-2807 is an effective tool compound achieving reversible inhibition of spermatogenesis @ScienceMagazine https://t.co/Hbr3IbTNFz